Eoin Mckinney T1D Epigenetics

The first introduction to psychology normally comes in the form of biology classes. Many biology students already come into class with at least basic knowledge of psychology. They understand that their genes determine how their bodies work, how they function and, to a certain extent, how they behave or what illnesses they might develop. But very few of these students have a clear understanding of what exactly DNA is, where it’s found in the body, why it causes problems, and how it can be manipulated or altered.

In the case of development, the genes passed from one generation to the next just have to survive. Genes are merely instructions for doing things. Humans, as all living things, are programmed through thousands of years of natural selection to participate in behavior that’s survival oriented. The foundation for this programming is the expression of certain genes that cause specific traits, such as aggressiveness, violence or sexuality. In the case of psychology, the genes that are passed on to us through our parents, grandparents, or other kin will determine such behavior.

In terms of understanding what is happening genetically, we are still in the age of molecular biology. Within this frame, genes are just packets of information carrying instructions. This is how humans, plants and animals have been growing for centuries. Nevertheless, in the past 50 years or so, a revolution in the field of psychology has happened known as molecular biology or genomics. Genomics provides a new lens through which we could see the relationships between behaviour and genes.

The molecular basis for human and behaviors memory is in fact quite simple – it’s all about the epigenome. The Epigenome is a cellular memory storage that determines whether a behavior is going to be expressed or not. Like all memory storage systems, it contains information that is “programmed” in advance by the genome.

What we now know is that the genetic material that determines behavior exists in all of us, but in varying amounts. The majority of the variations come from the variation in the copies of genes inside the mobile memory storage of the person. The copy of the gene which determines the behavior is called the epigome. It’s this specific copy that we call the epigenome.

The importance of the epigenome in psychology and its relationship to individual differences was shown in a landmark study on twins. For many years, autism research was based upon research on twins. However, it was discovered that there was substantial heritability (hitability) to behavior that existed between people who had identical twins but whose traits were very different. This study provided the first evidence of the significance of the epigenome in human behavior and its connection to abnormal behavioral disorders like autism.

Even though the significance of this Epigenome in psychology has been established, many in the psychological area are reluctant to accept its potential as a significant factor in mental illness. 1 reason for this is that it is difficult to define an actual genetic sequence or locus that causes a behavioral disorder. Another issue is that there are simply too many genetic differences between individuals to use a single DNA sequence to determine mental illness. Finally, even though the research on the Epigenome has been promising, more work needs to be done to find out the role that genetics play in complex diseases such as schizophrenia. If this finding holds true, it can be used as a basis for studying other complex diseases that have complicated genetic components.

If you’re interested in knowing more about Epigenetics and how it applies to psychology, I highly recommend that you follow the links below. My website discusses the exciting new technologies that are available now to better understand how Epigenetics affects behavior and the susceptibility to disease. You can even hear me speak on my epigenetics and autism blog. My research into Epigenetics is focused on understanding the environmental causes of disease, but I have also been involved in analyzing the relationship between Epigenetics and Autism. My future posts will also discuss diseases of the brain that can be affected by Epigenetics.